| Primary Identifier | IPR044509 | Type | Family |
| Short Name | RIC2/4 |
| description | This entry represents a group of plant CRIB domain-containing proteins including RIC2 and RIC4 from Arabidopsis. They belong to the RIC (ROP-interactive CRIB motif-containing protein) family. It has been shown that overexpression of RIC2 in tobacco germinating pollen reduces pollen tube elongation [].ROP1 and ROP6 have been shown to interact with RIC4, which promotes F-actin assembly. Together, they are involved in various processes of F-actin dynamics, cell growth, and plant/microbe interactions [].The RIC (ROP-interactive CRIB motif-containing protein) family members act as Rho GTPase (Rop) targets that function in distinct Rop signaling pathways []. RICs interact with multiple ROP GTPases via their conserved CRIB motif, and link ROP proteins to diverse target molecules that bind to their variable domains []. RICs share several consensus amino acid residues upstream of the CRIB motif and a consensus PSWMXDFK block downstream of the CRIB motif. Unlike other group members, members of group V, consisting of RIC4 and RIC2, lack the PSWMXDFK block and contain a relatively long N terminus in front of the CRIB motif and a short C terminus []. |
