| Primary Identifier | IPR020658 | Type | Family |
| Short Name | Ser/Thr_kinase_PLK3 |
| description | PLK3 (polo-like kinase 3) is a serine/threonine-protein kinase involved in cell cycle regulation, response to stress and Golgi disassembly [, , ]. It regulates angiogenesis and responses to DNA damage []. Activated PLK3 mediates Chk2 phosphorylation by ATM and the resulting checkpoint activation []. PLK3 phosphorylates DNA polymerase delta and may be involved in DNA repair. It also inhibits Cdc25c, thereby regulating the onset of mitosis [, ]. |
