|  Help  |  About  |  Contact Us

Protein Domain : Interleukin-1 receptor-associated kinase 1-binding protein 1

Primary Identifier  IPR030312 Type  Family
Short Name  IRAK1BP1
description  Interleukin-1 receptor-associated kinase 1-binding protein 1 (IRAK1BP1, also known as SIMPL) was originally identified in a yeast two-hybrid screen system []. In mice, IRAK1BP1 inhibits inflammation by promoting nuclear translocation of NF-kappaB p50 []. In Haliotis diversicolor, IRAK1BP1 plays an important role in the adult abalone immune system and might be essential in embryo and larval development in abalone [].

0 Child Features

1 Parent Features

3 Protein Domain Regions