Primary Identifier | IPR044427 | Type | Domain |
Short Name | LegAS4-like_SET |
description | LegAS4 () is a type IV secretion system effector of Legionella pneumophila. It contains a SET domain that is involved in the modification of Lys4 of histone H3 (H3K4) in the nucleolus of the host cell, thereby enhancing heterochromatic rDNA transcription. It also contains an ankyrin repeat domain of unknown function at its C-terminal region []. This entry represents the SET domain found in LegAS4 and related proteins. |