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Protein Domain : RNA polymerases, subunit N, zinc binding site

Primary Identifier  IPR020789 Type  Binding_site
Short Name  RNA_pol_suN_Zn-BS
description  In eukaryotes, there are three different forms of DNA-dependent RNA polymerases () transcribing different sets of genes. Each class of RNA polymerase is an assemblage of ten to twelve different polypeptides. In archaebacteria, there is generally a single form of RNA polymerase which also consists of an oligomeric assemblage of 10 to 13 polypeptides.Archaebacterial subunit N (gene rpoN) []is a small protein of about 8kDa, itis evolutionary related []to a 8.3kDa component shared by all three forms ofeukaryotic RNA polymerases (gene RPB10 in yeast and POLR2J in mammals) as wellas to African swine fever virus (ASFV) protein CP80R [].This signature spans the conserved region, which is located at theN-terminal extremity of these polymerase subunits; this region contains twocysteines that binds a zinc ion [].

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1 Protein Domain Regions