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Protein Domain : LIM domain-binding protein 1

Primary Identifier  IPR030167 Type  Family
Short Name  LDB1
description  LIM domain-binding protein 1 (LDB1) binds to the LIM domain of LIM homeodomain proteins which are transcriptional regulators. LDB1 is a multi-adaptor protein that mediates interactions between different classes of transcription factors and their co-regulators, and hence determine cell fate and differentiation []. In erythroid cells LDB1 is recruited to the beta-globin locus via LMO2 and is required for looping of the beta-globin locus control region (LCR) to the active beta-globin promoter [].
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0 Child Features

1 Parent Features

Trail: ProteinDomain

2 Protein Domain Regions

Trail: ProteinDomain




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