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Protein Domain : Nuclear mRNA export protein Sac3

Primary Identifier  IPR017173 Type  Family
Short Name  Sac3
description  This entry represents a mRNA export factor Sac3 from budding yeasts. Sac3 is a component of the TREX-2 complex (Sac3p-Thp1p-Sus1p-Cdc31p), which functions in transcription elongation and transcription-coupled mRNA export from the nucleus to the cytoplasm [, , ]. Its N terminus associates with Thp1 and Sem1 to form an mRNA-binding module, as well as with the export receptor Mex67, its C terminus interacts with Sus1, Cdc31 and the Nup1 nucleoporin, providing anchoring to the nuclear pore complex [].

0 Child Features

1 Parent Features

0 Protein Domain Regions