| Primary Identifier | IPR029196 | Type | Family |
| Short Name | TAPR1-like |
| description | This entry represents the Telomere attrition and p53 response 1 protein (TAPR1) from eukaryotes, including TAPR1 (also known as C16orf72/HAPSTR1) from human, which is a key multistress-responsive protein that functions as a negative regulator of TP53/P53 in the cellular response to telomere erosion and probably also DNA damage. It functions in cooperation with the E3 ubiquitin ligase HUWE1 which also promotes TAPR1's degradation [, ]. This family also includes the uncharacterised proteins from fungi, such as YJR056C from yeast. |
