| Primary Identifier | IPR044853 | Type | Homologous_superfamily |
| Short Name | G3DSA:1.10.10.1030 |
| description | This superfamily represents the HTH (helix-turn-helix) central domain from the metalloprotease IrrE, a central regulator of DNA damage repair in Deinococcaceae []. It is folded in a three-helix bundle, with the second and third helices forming the HTH motif. The IrrE HTH domain shows a high level of structural similarity to HTH domains of the Lrp/AsnC transcriptional regulatory family, although it is not located as expected at either C- or N-terminal of the protein. Its central location was suggested to endow it with some specific properties [].The domain is also found at the C-terminal of the catalytic domain of the protein ImmA (MEROPS identifier M78.001), a metallopeptidase containing an HEXXH zinc-binding motif. |
