Primary Identifier | IPR007899 | Type | Domain |
Short Name | CHAD_dom |
description | The CHAD (conserved histidine α-helical domain) is an uncharacteriseddomain, with a characteristic pattern of conserved histidines and othercharged residues. It is predicted to adopt an α-helical fold. The sequenceconservation pattern suggests that this domain is likely to contain two repeatunits, with at least 4 helices each, at its core. The conserved chargedresidues could form a strongly polar surface that could participate, either inmetal chelation, or act as phosphoacceptors [].Some proteins known to contain a CHAD domain are listed below:Escherichia coli uncharacterised protein YgiF.Mycobacterium tuberculosis uncharacterised protein Rv2226/MT2285. |