Primary Identifier | IPR042020 | Type | Domain |
Short Name | ING3_PHD |
description | This entry represents the PHD domain of ING3.Inhibitor of growth protein 3 (ING3) is a member of the ING family of tumour suppressors that regulate cell cycle progression, apoptosis and DNA repair []. ING3 is a component of the NuA4 histone acetyltransferase complex []and the SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome []. ING3 contains an N-terminal ING domain and a C-terminal plant homeodomain (PHD) finger. |