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Protein Domain : Melanoma-associated antigen D4

Primary Identifier  IPR030091 Type  Family
Short Name  MAGED4
description  The melanoma antigen (MAGE) protein family contains more than 25 members that share a conserved MAGE homology domain (MHD). Some MAGE antigens constitute important targets for antitumor immunotherapy. MAGED4 was originally identified as a glioma-specific antigen. It is predominantly expressed in glioma, but not in normal tissues except brain and ovary [, ]. MAGED4 contributes to proliferation, migration, and invasion of tumor cells in different types of cancer [, , ].

0 Child Features

1 Parent Features

0 Protein Domain Regions