| Primary Identifier | IPR042074 | Type | Homologous_superfamily |
| Short Name | M_arthritidis-der_mitogen_C |
| description | Mycoplasma arthritidis-derived mitogen (MA-Mit) adopts a completely α-helical structure consisting of ten alpha helices arranged in two orthogonal bundles. MA-Mit is a superantigen that can activate large fractions of T cells bearing particular TCR V-beta elements. Two MA-Mit molecules form an asymmetric dimer and cross-link two MHC antigens to form a dimerised MA-Mit-MHC complex [].This superfamily represents the C-terminal domain found in Mycoplasma arthritidis-derived mitogen. |
