| Primary Identifier | IPR039350 | Type | Family |
| Short Name | Prospero_homeodomain |
| description | Prospero-related proteins are conserved among metazoa and play important roles in development. They contain two characteristic conserved domains termed prospero domain 1 (PD1) and PD2 []. Drosophila Pros plays well-known roles in the establishment of cell fate during nervous system development []. In C. elegans, Prox1 functions as a major regulator of the glia-specific secretome that controls shape and function of sensory neurons []. Vertebrate Prox1 plays divergent roles in multiple organs by associating with nuclear receptors and modulating their transcriptional activities [, , ]. A second member of the family, Prox2, is present in vertebrates [, ]. |
