| Primary Identifier | IPR044737 | Type | Domain |
| Short Name | TopBP1_BRCT_1 |
| description | TopBP1, also termed DNA topoisomerase II-beta-binding protein 1, functions in DNA replication and damage response. It binds double-stranded DNA breaks and nicks as well as single-stranded DNA []. It has been shown to activate the ATR-ATRIP complex []. TopBP1 contains six copies of BRCT domain. The entry corresponds to the first BRCT domain, which is a protein-protein binding module []. |
