| Primary Identifier | IPR029391 | Type | Family |
| Short Name | CSN9_metazoa |
| description | This entry includes COP9 signalosome complex subunit 9, a component of the COP9 signalosome complex (CSN), which is conserved in all eukaryotes. The CSN complex is an essential regulator of the largest family of E3 ubiquitin ligases, the cullin-RING-ubiquitin ligases (CRLs). The CSN complex deactivates CRL by removing the ubiquitin-like tag NEDD8 (deneddylation) from the cullin subunit, or by binding to the deneddylated CRL, and preventing it interacting with E2 enzymes and ubiquitination substrates []. |
