Primary Identifier | IPR042320 | Type | Family |
Short Name | MMS22-like |
description | Methyl methanesulfonate-sensitivity protein 22-like (MMS22L) is a component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks []. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks [, ]. It may act by mediating the assembly of RAD51 filaments on ssDNA []. |