| Primary Identifier | IPR033076 | Type | Family |
| Short Name | CD36_chordates |
| description | CD36 (also known as platelet glycoprotein 4) is a recognition receptor that binds polyanionic ligands of both pathogen and self-origin, and is implicated in the pathogenesis of atherosclerosis and Alzheimer's disease [, ]. CD36 plays an important role in innate immunity and in the phagocytic uptake of multiple pathogens including malaria []. It has also been implicated in several aspects related to fatty acid metabolism [].Mutations in the CD36 gene cause platelet glycoprotein IV deficiency (PG4D), a disorder characterised by macrothrombocytopenia without notable hemostatic problems and bleeding tendency [, ]. |
