|  Help  |  About  |  Contact Us

Protein Domain : Interferon regulatory factor 2

Primary Identifier  IPR031218 Type  Family
Short Name  IRF2
description  Interferon regulatory factor 2 (IRF2) is a multifunctional transcription factor that plays a pivotal role in regulation of apoptosis and cell cycle control [, , ]. It also plays an important role in modulating cellular responses to interferon (IFN) and viral infection []. It has an antagonistic role to IRF1 in transcriptional regulation of IFN and ISG genes []. While IRF1 acts as a positive regulator, IRF2 is known to repress IFN-mediated gene expression.

0 Child Features

1 Parent Features

11 Protein Domain Regions