Primary Identifier | IPR031218 | Type | Family |
Short Name | IRF2 |
description | Interferon regulatory factor 2 (IRF2) is a multifunctional transcription factor that plays a pivotal role in regulation of apoptosis and cell cycle control [, , ]. It also plays an important role in modulating cellular responses to interferon (IFN) and viral infection []. It has an antagonistic role to IRF1 in transcriptional regulation of IFN and ISG genes []. While IRF1 acts as a positive regulator, IRF2 is known to repress IFN-mediated gene expression. |