Primary Identifier | IPR042425 | Type | Family |
Short Name | APCDD1 |
description | APCDD1 (Adenomatosis polyposis coli down-regulated 1) is directly regulated by the beta-catenin/Tcf complex, and its elevated expression promotes proliferation of colonic epithelial cells in vitro and in vivo []. APCDD1 has an N-terminal signal-peptide and a C-terminal transmembrane region. APCDD1 is expressed in a broad repertoire of cell types, indicating that it may regulate a diverse range of biological processes controlled by Wnt signalling []. |