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Protein Domain : Isthmin

Primary Identifier  IPR042413 Type  Family
Short Name  ISM
description  This entry represents Isthmin, including ISM1 and ISM2 from humans. It is a secreted angiogenesis inhibitor that inhibits tumour growth in mice []. Zebrafish ISM1 is required for normal generation of hematopoietic stem and progenitor cells and their downstream progeny [].
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