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Protein Domain : Plastin-1

Primary Identifier  IPR030235 Type  Family
Short Name  PLS1
description  Plastin-1 is an actin-bundling protein of the microvilli and stereocilia [, ]. It is the most abundant actin-bundling protein of stereocilia. Mutations in the human PLS1 gene may be associated with relatively mild and progressive forms of hearing loss []. Plastin-1 mediates liquid packing of actin, which is required for stereocilia growth [].

0 Child Features

1 Parent Features

4 Protein Domain Regions