Primary Identifier | IPR030235 | Type | Family |
Short Name | PLS1 |
description | Plastin-1 is an actin-bundling protein of the microvilli and stereocilia [, ]. It is the most abundant actin-bundling protein of stereocilia. Mutations in the human PLS1 gene may be associated with relatively mild and progressive forms of hearing loss []. Plastin-1 mediates liquid packing of actin, which is required for stereocilia growth []. |