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Protein Domain : Activated CDC42 kinase 1

Primary Identifier  IPR030220 Type  Family
Short Name  Ack1
description  Activated CDC42 kinase 1 (Ack1) is a non-receptor tyrosine kinase (NRTK) that is implicated in metastatic behaviour, cell spreading and migration, and epidermal growth factor receptor (EGFR) signalling []. It interacts with a number of transmembrane receptor tyrosine kinases and is involved in several cell signalling pathways. Its activation has been linked to cancer progression [].

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16 Protein Domain Regions