| Primary Identifier | IPR029287 | Type | Domain |
| Short Name | RAE-1 |
| description | Members of this group are known as retinoic acid early inducible proteins (RAE-1) [, ]. They are ligands for the activating immunoreceptor NKG2D, which is widely expressed on natural killer cells, T cells, and macrophages []. There is a considerable diversity of NKG2D ligands. In mice, the ligands include, among others, five members of the retinoic acid early inducible gene 1 (RAE-1; α-ε) [].RAE-1 proteins are distant major histocompatibility complex (MHC) class I homologues, comprising isolated alpha1-alpha2 platform domains []. |
