| Primary Identifier | IPR020935 | Type | Conserved_site |
| Short Name | PdiEstase_YfcE_CS |
| description | This entry represents a short conserved sequence region found in a family of short, hydrophilic proteins that are all known or suspected phosphodiestreases. The best characterised of these is YfcE from Escherichia coli []. The physiological substrate for this protein is not known, though it is capable of hydrolysing phosphodiesters bonds in the artificial chromogenic substrate bis-p-nitrophenyl phosphate. YfcE is a tetrameric, managanese-binding protein where each monomer forms a β-sandwich fold similar to other metallophosphatases. The member MJ0936 from Methanocaldococcus jannaschii (Methanococcus jannaschii), was shown []to act on model phosphodiesterase substrates; a divalent cation was required. |
