| Primary Identifier | IPR032908 | Type | Family |
| Short Name | LpxT |
| description | This entry represents lipid A 1-diphosphate synthase LpxT (also known as YeiU) from Enterobacteriaceae. It is involved in the modification of the lipid A domain of lipopolysaccharide (LPS), which is part of Gram-negative bacteria outer membrane. Variation of the lipid A domain of LPS serves to promote bacterial resistance []. LpxT transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1-diphosphate and contributes to the recycling of undecaprenyl phosphate (C55-P) []. It also has low undecaprenyl-diphosphate phosphatase activity in vitro[]. |
