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Protein Domain : Thialysine N-epsilon-acetyltransferase

Primary Identifier  IPR032959 Type  Family
Short Name  SAT2
description  SAT2 (also known as spermidine/spermine-N1-acetyltransferase-2, SSAT2) was originally identified based on homology to SSAT1, a protein involved in polyamine catabolism. However, SSAT2 does not acelylate polyamines, but instead acetylates thialysine, a structural analogue of L-lysine []. The role of SSAT2 is still unclear []. It can function as a transcriptional coactivator for NF-kappaB []. It seems to be an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha [].

0 Child Features

0 Parent Features

3 Protein Domain Regions