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Protein Domain : Receptor-interacting serine/threonine-protein kinase 2

Primary Identifier  IPR017322 Type  Family
Short Name  Rcpt-int_Ser/Thr_kinase-2
description  This entry represents receptor-interacting serine/threonine-protein kinase 2 (RIP2), which functions in the phosphorylation () of its protein target. This enzyme activates pro-caspase-1 and pro-caspase-8, and it thought to potentiate CASP8-mediated apoptosis []. It also activates NF-kappa-B. RIP2 undergoes autophosphorylation; it is phosphorylated upon DNA damage, probably by ATM or ATR.
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2 Protein Domain Regions

Trail: ProteinDomain




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