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Protein Domain : DNA-binding, RFXANK

Primary Identifier  IPR017362 Type  Family
Short Name  DNA-bd_RFXANK
description  This group represents the DNA-binding protein RFXANK which activates transcription from class II MHC promoters, requiring the activity of the MHC class II transactivator/CIITA. Deficiency is the commonest cause of bare lymphocyte syndrome (the absence of MHC class II transcription and humoral- and cellular-mediated immune responses to foreign antigens) [, ].

0 Child Features

0 Parent Features

4 Protein Domain Regions