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Protein Domain : Cadherin-related family member 5

Primary Identifier  IPR030326 Type  Family
Short Name  Mucdhl
description  Cadherin-related family member 5 (also known as Mucin and cadherin like, Mucdhl or MUPCDH) belongs to the protocadherins subgroup of the cadherin superfamily, whose members are membranous glycoproteins mediating Ca2+-dependent cell-to-cell adhesion []. The Mucdhl gene encodes several splicing isoforms that are mostly expressed in the kidney, liver, and gut [, , ]. Mucdhl is associated with Cdx2 and beta-catenin, and is linked to colorectal carcinogenesis []. It interacts with PCDH24 and plays a role in the brush border assembly [].This entry also includes cadherin-86C from the fruit fly Drosophila melanogaster.

0 Child Features

0 Parent Features

4 Protein Domain Regions