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Protein Domain : LETM1/MDM38-like

Primary Identifier  IPR044202 Type  Family
Short Name  LETM1/MDM38-like
description  This family represents a group of LETM1-like mitochondrial inner membrane proteins, including LETM1/LETM2 from mammals and YLH47/MDM38 from yeastsLETM1 is a proton/calcium antiporter that mediates proton-dependent calcium efflux from mitochondrion []. LETM2 is preferentially expressed in testis and sperm. In humans, deletion of LETM1 causes Wolf-Hirschhorn syndrome [].

0 Child Features

0 Parent Features

8 Protein Domain Regions