|  Help  |  About  |  Contact Us

Protein Domain : Junctional adhesion molecule B

Primary Identifier  IPR042625 Type  Family
Short Name  JAM2
description  Junctional adhesion molecule 2 (JAM2), also known as VE-JAM or JAM-B, is a type I integral membrane protein that contains two Ig-like folds and three N-linked glycosylation sites in the extracellular domain []. JAM2 was initially identified as an endothelial adhesion molecule that plays a role in the architecture of interendothelial junctions and control leukocyte migration to inflammatory sites []. JAM2 interacts with T, NK, and dendritic cells through JAM3 [].

0 Child Features

0 Parent Features

3 Protein Domain Regions