| Primary Identifier | IPR029641 | Type | Family |
| Short Name | APC16 |
| description | The anaphase promoting complex/cyclosome (APC/C) is a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C consists of thirteen different subunits and, in somatic cells, has two co-activators: Cdc20 and Cdh1 (also known as Fzr1), which associate with the APC/C core at defined stages of the cell cycle. APC/C is only active between metaphase and the end of the next G1 phase. During this time, APC/CCdc20 initiates anaphase and mitotic exit,while APC/CCdh1 contributes to mitotic exit and establishment of a stable G1 state []. This entry represents the APC/C subunit 16 []. |
