| Primary Identifier | IPR027013 | Type | Family |
| Short Name | Caskin-1/2 |
| description | Caskin-1 and Caskin-2 are multidomain proteins containing six N-terminal ankyrin repeats, a single SH3 domain, and two sterile alpha motif (SAM) domains followed by a long proline-rich sequence and a short conserved C-terminal domain. Caskin-1 may link the scaffolding protein CASK to downstream intracellular effectors []. Caskin-1 polymerises, via the tandem SAM domains, to form long, 8 nM wide fibres, upon which other proteins can assemble []. |
