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Protein Domain : Syntenin-1

Primary Identifier  IPR030528 Type  Family
Short Name  SDCBP
description  Syntenin-1 was originally identified as a syndecan-binding PDZ protein []. Later, Syntenin-1 is found to be a scaffolding protein that interacts with several membrane receptors, such as the lymphocyte receptor CD6 and the interleukin 5 (IL-5) receptor [, , ]. It has diverse cellular roles including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis [, , , ]. Its structure has been solved [, ].

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17 Protein Domain Regions