Primary Identifier | IPR030528 | Type | Family |
Short Name | SDCBP |
description | Syntenin-1 was originally identified as a syndecan-binding PDZ protein []. Later, Syntenin-1 is found to be a scaffolding protein that interacts with several membrane receptors, such as the lymphocyte receptor CD6 and the interleukin 5 (IL-5) receptor [, , ]. It has diverse cellular roles including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis [, , , ]. Its structure has been solved [, ]. |