| Primary Identifier | IPR040181 | Type | Family |
| Short Name | PKHG5/7 |
| description | This entry includes pleckstrin homology domain-containing family G member 5/7 (PKHG5/7). PKHG5 is a guanine nucleotide exchange factor. PKHG5, also known as Plekhg5, has been shown to activate RHOA []. Plekhg5-depleted cultured motoneurons show defective axon growth and impaired autophagy of synaptic vesicles, which can be rescued by constitutively active Rab26 []. The function of PKHG7 is not clear. |
