Primary Identifier | IPR029825 | Type | Family |
Short Name | ATF1 |
description | ATF1, CREB, and CREM constitute a subfamily of the basic leucine zipper transcription factors, and they activate gene expression by binding as homo- or heterodimers to the cAMP response elements (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'). ATF1 (activating transcription factor 1) plays important roles in cell survival and proliferation [, ]. It is required for the development of preimplantation embryos []. |