| Primary Identifier | IPR030856 | Type | Family |
| Short Name | RcsC |
| description | Sensor histidine kinase RcsC forms part of a phosphorelay signal transduction pathway with RcsD and RcsB. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals []. The phosphoryl group is then transferred to the response regulator RcsB. The system controls transcription of numerous genes. It was first identified by its role in the regulation of capsular polysaccharide or colanic acid synthesis [, , ]. Pathways regulated by the Rcs system include maintenance of cell wall integrity, cell division,motility, and virulence [, , ]. A novel signaling pathway that depends on RcsC, but independent of RcsD and RcsB, has also been described []. |
