Primary Identifier | IPR029843 | Type | Family |
Short Name | CDKN1B |
description | Cyclin-dependent kinase inhibitor 1B (CDKN1B, also known as p27Kip1) controls cell proliferation by binding to and regulating the activity of cyclin-dependent kinases (Cdks) []. It is also involved in cell migration through binding and regulation of RhoA or stathmin [, , ]. It also inhibits DNA replication by binding to the DNA replication licensing factor MCM7 []. |