Primary Identifier | IPR029832 | Type | Family |
Short Name | TEF/VBP |
description | Thyrotroph embryonic factor (TEF) belongs to the PAR (Proline and Acidic amino acid-Rich basic leucine ZIPper) transcription factor family, which consists of HLF, DBP and TEF proteins []. TEF may bind DNA specifically as a homodimer or as a heterodimer with other PAR factors. It binds to the consensus sequence 5'-GTTACGTAAT-3' []. TEF is involved in the regulation of apoptotic proteins [, ]. In chicken it is known as VBP, which binds to and transactivates the vitellogenin II (VTG2) promoter [, ]. |