| Primary Identifier | IPR001061 | Type | Family |
| Short Name | TAGLN2 |
| description | Transgelin belongs to the calponin family, whose members have an N-terminal calponin homology domain (CH) and the C-terminal calponin-like repeat. Transgelin (also known as SM22) is an actin binding protein localised to the cytoskeletal apparatus []. Transgelin is required in agonist-induced smooth muscle contraction and is involved in cell migration [, ]. It has tumour suppressive functions in certain cells [, ]. The function of transgelin-2, also known as SM22-beta, is not clear. It seem to have a unique developmentally regulated pattern of expression []. |
