Primary Identifier | IPR039040 | Type | Family |
Short Name | NAB_fam |
description | Proteins in this family are transcriptional regulators, including Nab (NGFI-A-binding protein) from Drosophila and Nab1/2 from mammals. Nab1 and Nab2 are co-repressors that specifically interact with and repress transcription mediated by the three members of the NGFI-A (Egr-1, Krox24, zif/268) family of eukaryotic (metazoa) transcription factors []. Drosophila Nab controls the activity of zinc-finger transcription factors, such as Squeeze and Rotund, in Drosophila development []. |