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Protein Domain : Rho GTPase-activating protein 6/36

Primary Identifier  IPR037863 Type  Family
Short Name  RHOGAP6/36
description  Rho GTPase activating protein 6 (ArhGAP6/RHOGAP6) shows GAP activity towards RhoA, but not towards Cdc42 and Rac1 []. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS); MLS is a severe X-linked developmental disorder [].This family also includes ARHGAP36, which is a potent antagonist of PKA signalling [].

1 Child Features

0 Parent Features

12 Protein Domain Regions