| Primary Identifier | IPR030750 | Type | Family |
| Short Name | RGL3 |
| description | RGL3 (RalGDS-like 3) belongs to the Ral GDP dissociation stimulator (RalGDS) family []. RGL3 functions as an exchange factor for Ral and may serve as a downstream effector for both Rit and Ras [, ].RalGDS family members can act both as Ras effectors and as guanine nucleotide exchange factors (GEFs) for Ral. They act downstream of Ras and bind to the GTP-bound active form of Ras or Ras family members. They also promote the GDP to GTP exchange for Ral small GTPase, member of the Ras family []. Due to their double action, the RalGDS proteins bridge Ras and Ral []. |
