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Protein Domain : Transcriptional repressor p66

Primary Identifier  IPR040386 Type  Family
Short Name  P66
description  P66alpha and P66beta interact with MBDs (methyl-binding domain-containing proteins) via a coiled-coil region on each []. P66 and MBD2 form a complex with the nucleosome remodeling and deacetylation (NuRD) complex. This MBD2-NuRD complex recognizes methylated DNA and silences expression of associated genes through histone deacetylase and nucleosome remodeling functions [, ].
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Trail: ProteinDomain




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