| Primary Identifier | IPR027412 | Type | Homologous_superfamily |
| Short Name | Gp9_C_dom_sf |
| description | The Bacteriophage T4 is a double-stranded, structurally complex virus that infects Escherichia coli. Gene product 9 (Gp9) connects the long tail fibres to the baseplate, and triggers baseplate reorganisation and tail contraction after virus attachment to the host cell. The Gp9 protein forms a homotrimer, with each monomer having three domains: the N-terminal α-helical domain forms a triple coiled coil, the middle domain is a mixed, seven-stranded beta sandwich with a unique fold, and the C-terminal domain is a eight-stranded β-sandwich with similarity to jellyroll viral capsid protein structures []. The flexible loops that occur between domains may enable the conformational changes necessary during infection. This superfamily represents the Gp9 C-terminal domain. |
