Primary Identifier | IPR040474 | Type | Domain |
Short Name | Get5_C |
description | Tail-anchored trans-membrane proteins are targeted to membranes post-translationally. The proteins Get4 and Get5 form an obligate complex that catalyzes the transfer of tail-anchored proteins destined to the endoplasmic reticulum from Sgt2 to the cytosolic targeting factor Get3. This is the carboxyl domain of Get5 (also known as Mdy2), a homodimerization domain, resulting in a heterotetrameric Get4/Get5 complex []. |