| Primary Identifier | IPR005931 | Type | Family |
| Short Name | P5CDH/ALDH4A1 |
| description | This entry represents one of two related branches of delta-1-pyrroline-5-carboxylate dehydrogenase (P5CDH, ; also known as ALDH4A1 in humans). It is responsible for the NAD+-dependent, irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate [, ]. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. P5CDH is a mitochondrial homodimer and a member of the aldehyde dehydrogenase (ALDH) protein superfamily. Also included in this entry is the Aldh17 Drosophila melanogaster (Q9VUC0) P5CDH and similar sequences [, ]. |
