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Protein Domain : Carboxymethylenebutenolidase homolog

Primary Identifier  IPR042946 Type  Family
Short Name  CMBL
description  Carboxymethylenebutenolidase (CMBL) is a human homologue of Pseudomonas dienelactone hydrolase involved in the bacterial halocatechol degradation pathway.It is a cysteine hydrolase that can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine [].This entry also includes uncharacterised DLH domain-containing proteins from plants.

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0 Parent Features

4 Protein Domain Regions