Primary Identifier | IPR040363 | Type | Family |
Short Name | HMBOX1 |
description | HMBOX1 binds to 5'-TTAGGG-3' repeats in telomeric DNA and may play a role in recruitment of the telomerase complex to telomeres [, ]. It also plays a role in the alternative lengthening of telomeres (ALT) pathway in telomerase-negative cells where it promotes formation and/or maintenance of ALT-associated promyelocytic leukemia bodies (APBs) []. |