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Protein Domain : Homeobox-containing protein 1

Primary Identifier  IPR040363 Type  Family
Short Name  HMBOX1
description  HMBOX1 binds to 5'-TTAGGG-3' repeats in telomeric DNA and may play a role in recruitment of the telomerase complex to telomeres [, ]. It also plays a role in the alternative lengthening of telomeres (ALT) pathway in telomerase-negative cells where it promotes formation and/or maintenance of ALT-associated promyelocytic leukemia bodies (APBs) [].

0 Child Features

0 Parent Features

9 Protein Domain Regions